The main bioflavonoid complex found in milk thistle seeds, silymarin has been widespread in use for thousands of years to improve bile transport and support the liver, spleen and kidneys. It enhances liver cell detoxification by preventing the depletion of glutathione and by binding to liver cells, protecting them from exposure to chemicals and toxins. Silymarin is also able to increase unique protein synthesis within cells that protect them from free radical damage.
Liver Support and Detoxification†
Silymarin protects the liver through various functions: acting as an antioxidant;1 preventing lipid oxidation;2 balancing Phase I detoxification; enhancing glucuronidation, to help eliminate excess hormones;3,4 and preventing the depletion of glutathione.5 Silymarin also supports a normal inflammatory response by inhibiting leukotriene and prostaglandin synthesis, quieting immune mast cells and neutrophils,6-9 as well as increasing the production of cellular proteins that promote cell regeneration.10 Clinical studies have also demonstrated silymarin can also boost immune health.11-13
Silymarin has been reported to protect the health of kidneys from free radical stress caused by exposure to heavy metals.14 Pre-supplementation with silymarin was also found to significantly protect cells from free radical damage induced by toxins, in a dose-dependent manner.15 Dietary supplementation of silymarin has also been found to protect kidney function and promote a normal response to inflammation.16
Nerve Cell Function and Brain Health†
Animal research has demonstrated a significant reduction in levels of amyloid beta in the brain and improvement in behavior when preventively treated with a powdered diet containing 0.1% silymarin over 6 months. Silymarin-treated animals also showed calmer behavior than controls.17 In another study, silymarin was found to help counteract oxidative stress in animals to support blood sugar and nervous system health.18
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease